here i think:
Polygenitus
You guys had me at Wrath of God. I dies to wrath, so why are we still having this discussion?
You can:
Wrath him
Obliterate him
Counter him
Upheaval him
Meddling Mage'im
Cranial Extract'im
Wash him out
Humility Him
If all above fails, you can most definitely build a decent deck and ignore him.
wing shards?
(only my favorite card ever)
doesnt exactly kill him but you can use ability of Karn Liberated to restart the game and you can get rid of the progenitus
Would a World Slayer work against it?
Absolutely.
Fluttershy is best pony.
I don't think the person who made that post in 2009 in paying attention to this thread anymore.
Also what are you talking about? Quicksilver Amulet and Dragon Arch do nothing for Progenitus in EDH, your Commander starts in the Command Zone, not your hand.